What Adam Is Reading
Three Legal Drugs and a Rowing Machine
A Division 1 rower's supplement stack sounded like nonsense. The literature said otherwise. A lesson in whose skepticism you can trust.
Multi-source synthesis · Caffeine, sodium bicarbonate, beta-alanine · August 2026

A friend of my son's rows at the Division 1 level. He mentioned that, at his coach's instruction, he takes large doses of caffeine, sodium bicarbonate, and beta-alanine to improve performance. As someone who spends his days with patients who have complex chronic disease, my automatic thought was that this was nonsense. Loading a healthy body with grams of anything to chase a theoretical metabolic edge is the setup for a case report, not a race plan.

Interestingly, the literature proved me wrong. All three have a real evidence base, with data suggesting they help maximize performance in eight-to-ten-minute rowing races. Though the measurable gains are small (0.5 to 2.0 percent improvements in performance), in a sport decided by fractions of a boat length, small is the whole game.

A 2000 meter row is aerobic at its core and acidosis-limited at its edges. That is the physiological sweet spot where these compounds do measurable work. So I did what I would tell a resident to do. I went to the literature with him and started pulling data.


What the evidence actually says
1
Caffeine
What holds up

Caffeine is the best-supported ergogenic aid in rowing, full stop. A 2023 network meta-analysis of 71 rowing studies ranked it the top acute nutritional intervention. In elite rowers, 3 mg/kg improved six-minute maximal performance, with the benefit landing in the final four to six minutes, right where a race is won. The effective dose is 3 to 6 mg/kg. His 300 to 400 mg lands around 3.5 to 4.5 mg/kg for an open-weight rower. That is inside the range, not above it.

The real long-term cost

Not the kidneys. Large cohorts tie habitual coffee intake to lower rates of chronic kidney disease and stones, not higher. The honest chronic problems are tolerance, dependence, dose creep, and wrecked sleep, which is itself performance-limiting. The failure mode is not organ damage. It is needing more next year to feel the same thing.

Solid
2
Sodium bicarbonate
What holds up

Bicarbonate buffers acid in the space outside the cell, and 0.3 g/kg is the best-supported dose. It earns its keep in short, maximal, acidosis-limited efforts. The catch is that the one trial testing it head to head in elite rowers found no benefit from bicarbonate alone. It did not blunt caffeine, but it did not add anything either.

The real long-term cost

This is the one I would reconsider. The rowing-specific benefit is the weakest of the three, and the chronic cost is the most tangible. It is a recurring sodium and alkali load, and controlled data show it can nudge up diastolic blood pressure and drive volume expansion. My instinct was to worry about stones. That instinct was wrong. Alkalinizing the urine is how we prevent uric acid and cystine stones, so bicarbonate is neutral to protective there. The blood pressure and volume effects are the real story.

Mostly Solid
3
Beta-alanine
What holds up

Beta-alanine raises intramuscular carnosine, a buffer that works inside the cell. It is genuinely ergogenic for efforts of one to four minutes, and 2000 meter rowing is one of the events with strong evidence behind it. A meta-analysis in trained young men found the effect strongest for four to ten minute efforts at higher daily doses. It works on accumulated dose over weeks, not on a race-day pill.

The real long-term cost

Almost none, which is the surprise. A risk assessment across 101 human and 50 animal studies found paresthesia, the harmless tingle after a big single dose, as the only adverse effect. No dropouts, no meaningful liver signal, no taurine depletion. The only real downside is commitment. It does nothing until you have taken it daily for four weeks, so it is a standing habit rather than a tool.

Solid
The stack in one line. Caffeine is the one that works and is fine at his dose. Beta-alanine is the one that works a little and is remarkably clean. Bicarbonate is the one doing the least for the most physiologic rent. All three are WADA-legal, which makes contamination of a multi-ingredient tub, not the compounds themselves, the likeliest route to a failed test.
So What

Twenty years with older, sicker patients does not transfer to a healthy twenty-year-old with a four-year competition window. Therapy is contextual. What is unsafe in patients with multiorgan disease can be reasonable in an athlete with none.

The trade-offs still have to be counted. Four to five years of daily baking soda and beta-alanine, with caffeine dosed around races, is a real exposure, not a free one. But the small edge it offers a rowing team may be a trade worth making.

Sources

Synthesis: OpenEvidence literature query, agent-by-agent analysis of caffeine, sodium bicarbonate, and beta-alanine as ergogenic aids in rowing. openevidence.com

Caffeine, rowing: Held S, et al. Acute and Chronic Performance Enhancement in Rowing: A Network Meta-Analytical Approach. Sports Medicine, 2023. PMID 37097415

Caffeine vs. bicarbonate, elite rowers: Christensen PM, et al. Caffeine, but Not Bicarbonate, Improves 6 Min Maximal Performance in Elite Rowers. Appl Physiol Nutr Metab, 2014. PMID 24999004

Caffeine dose: Guest NS, et al. ISSN Position Stand: Caffeine and Exercise Performance. J Int Soc Sports Nutr, 2021. PMID 33388079

Caffeine side effects: Negaresh R, et al. Caffeine Use in Sport: Systematic Review and Meta-Analysis of Acute Side Effects. Sports Medicine, 2026. PMID 42033594

Buffering agents, dose: Lancha Junior AH, et al. Nutritional Strategies to Modulate Buffering Capacity. Sports Medicine, 2015. PMID 26553493

Bicarbonate, volume/BP: Beaume J, et al. Sodium Bicarbonate Prescription and Extracellular Volume Increase (AlcalUN). Clin Pharmacol Ther, 2022. PMID 34564842

Beta-alanine, rowing: Brisola GMP, Zagatto AM. Ergogenic Effects of Beta-Alanine on Different Sports Modalities. J Strength Cond Res, 2019. PMID 30431532

Beta-alanine safety: Dolan E, et al. A Systematic Risk Assessment and Meta-Analysis on Oral Beta-Alanine Supplementation. Advances in Nutrition, 2019. PMID 30980076