A friend of my son's rows at the Division 1 level. He mentioned that, at his coach's instruction, he takes large doses of caffeine, sodium bicarbonate, and beta-alanine to improve performance. As someone who spends his days with patients who have complex chronic disease, my automatic thought was that this was nonsense. Loading a healthy body with grams of anything to chase a theoretical metabolic edge is the setup for a case report, not a race plan.
Interestingly, the literature proved me wrong. All three have a real evidence base, with data suggesting they help maximize performance in eight-to-ten-minute rowing races. Though the measurable gains are small (0.5 to 2.0 percent improvements in performance), in a sport decided by fractions of a boat length, small is the whole game.
A 2000 meter row is aerobic at its core and acidosis-limited at its edges. That is the physiological sweet spot where these compounds do measurable work. So I did what I would tell a resident to do. I went to the literature with him and started pulling data.
Caffeine is the best-supported ergogenic aid in rowing, full stop. A 2023 network meta-analysis of 71 rowing studies ranked it the top acute nutritional intervention. In elite rowers, 3 mg/kg improved six-minute maximal performance, with the benefit landing in the final four to six minutes, right where a race is won. The effective dose is 3 to 6 mg/kg. His 300 to 400 mg lands around 3.5 to 4.5 mg/kg for an open-weight rower. That is inside the range, not above it.
The real long-term costNot the kidneys. Large cohorts tie habitual coffee intake to lower rates of chronic kidney disease and stones, not higher. The honest chronic problems are tolerance, dependence, dose creep, and wrecked sleep, which is itself performance-limiting. The failure mode is not organ damage. It is needing more next year to feel the same thing.
Bicarbonate buffers acid in the space outside the cell, and 0.3 g/kg is the best-supported dose. It earns its keep in short, maximal, acidosis-limited efforts. The catch is that the one trial testing it head to head in elite rowers found no benefit from bicarbonate alone. It did not blunt caffeine, but it did not add anything either.
The real long-term costThis is the one I would reconsider. The rowing-specific benefit is the weakest of the three, and the chronic cost is the most tangible. It is a recurring sodium and alkali load, and controlled data show it can nudge up diastolic blood pressure and drive volume expansion. My instinct was to worry about stones. That instinct was wrong. Alkalinizing the urine is how we prevent uric acid and cystine stones, so bicarbonate is neutral to protective there. The blood pressure and volume effects are the real story.
Beta-alanine raises intramuscular carnosine, a buffer that works inside the cell. It is genuinely ergogenic for efforts of one to four minutes, and 2000 meter rowing is one of the events with strong evidence behind it. A meta-analysis in trained young men found the effect strongest for four to ten minute efforts at higher daily doses. It works on accumulated dose over weeks, not on a race-day pill.
The real long-term costAlmost none, which is the surprise. A risk assessment across 101 human and 50 animal studies found paresthesia, the harmless tingle after a big single dose, as the only adverse effect. No dropouts, no meaningful liver signal, no taurine depletion. The only real downside is commitment. It does nothing until you have taken it daily for four weeks, so it is a standing habit rather than a tool.
Twenty years with older, sicker patients does not transfer to a healthy twenty-year-old with a four-year competition window. Therapy is contextual. What is unsafe in patients with multiorgan disease can be reasonable in an athlete with none.
Sources
Synthesis: OpenEvidence literature query, agent-by-agent analysis of caffeine, sodium bicarbonate, and beta-alanine as ergogenic aids in rowing. openevidence.com
Caffeine, rowing: Held S, et al. Acute and Chronic Performance Enhancement in Rowing: A Network Meta-Analytical Approach. Sports Medicine, 2023. PMID 37097415
Caffeine vs. bicarbonate, elite rowers: Christensen PM, et al. Caffeine, but Not Bicarbonate, Improves 6 Min Maximal Performance in Elite Rowers. Appl Physiol Nutr Metab, 2014. PMID 24999004
Caffeine dose: Guest NS, et al. ISSN Position Stand: Caffeine and Exercise Performance. J Int Soc Sports Nutr, 2021. PMID 33388079
Caffeine side effects: Negaresh R, et al. Caffeine Use in Sport: Systematic Review and Meta-Analysis of Acute Side Effects. Sports Medicine, 2026. PMID 42033594
Buffering agents, dose: Lancha Junior AH, et al. Nutritional Strategies to Modulate Buffering Capacity. Sports Medicine, 2015. PMID 26553493
Bicarbonate, volume/BP: Beaume J, et al. Sodium Bicarbonate Prescription and Extracellular Volume Increase (AlcalUN). Clin Pharmacol Ther, 2022. PMID 34564842
Beta-alanine, rowing: Brisola GMP, Zagatto AM. Ergogenic Effects of Beta-Alanine on Different Sports Modalities. J Strength Cond Res, 2019. PMID 30431532
Beta-alanine safety: Dolan E, et al. A Systematic Risk Assessment and Meta-Analysis on Oral Beta-Alanine Supplementation. Advances in Nutrition, 2019. PMID 30980076