Weekly newsletter & archive

What Adam Is Reading

The Brain on a Pep Talk Single-source science summary of Cascio, O'Donnell, Tinney, Lieberman, Taylor, Strecher & Falk, Soc Cogn Affect Neurosci 2016;11(4):621-629 (DOI 10.1093/scan/nsv136), an fMRI study of self-affirmation in 67 sedentary adults (33 affirmed, 28 control). Affirmed participants showed greater reward (ventral striatum + VMPFC) and self-processing (MPFC + PCC) activity when reflecting on future-oriented core values (reward P=0.002, self-processing P=0.015); no group difference for past-oriented scenarios. One-month accelerometer follow-up showed steeper declines in sedentary behavior in the affirmed group (P=0.008), and neural activity during affirmation predicted less subsequent sitting (betas approx -0.26 / -0.27, P=0.030 / 0.039). Verdicts: Solid on the core neural finding, Mostly Solid on the brain-predicts-behavior link (small n, modest effects, reverse-inference and leaky-control caveats the authors name themselves). The Coffee Knows What Time It Is Single-source review of Wang, Ma, Sun, Qi et al., European Heart Journal 2025;46(8):749-759 (DOI 10.1093/eurheartj/ehae871). NHANES cluster analysis of 40,725 US adults finds a morning-type coffee pattern (36%) associated with lower all-cause (HR 0.84) and CVD mortality (HR 0.69) vs non-drinkers, while an all-day-type pattern (14%) shows no association, independent of amount; dose-response only in morning drinkers (P-interaction 0.031). Validated in WLVS/MLVS 7-day records. Verdict Mostly Solid: strong replicated signal, but observational, single dietary snapshot, unadjusted shift work/wake time, healthy-user and reverse-causation confounding. Added to the Coffee Ledger. The Coffee Ledger Adam's Coffee Confirmation Bias Corner, tallied, in two tiers. Tier one: every coffee and caffeine study WAiR has covered since 2020, with findings, the caveat attached at the time, and links to the issue and deep dive. Tier two, added September 2026: the foundational evidence that has never appeared in the newsletter, found by checking the Cork microbiome study's 97 references against the full text of all 548 documents in the archive. Includes a decaf scorecard, a preparation axis, and the recurring caveats. Updated whenever a new coffee study is reviewed. One Minute on the Stairs Single-source review of Morales, Wong, Moore and Kressler, Experimental Physiology 2024 (print 2026), PMID 39705060: one minute of light-intensity stair stepping 57 minutes into an evening OGTT, 30 healthy adults, randomized crossover. Lead finding: a few published protocol details differ from the prospective registration NCT05617157 (stair bout at 57 vs 28 min after the drink, a different glucose sampling schedule, insulin registered as a secondary outcome but not reported, and a different primary endpoint), and the paper does not cite the registration or note the change. The acute dip is real and lasts about twenty minutes (Mostly Solid); the whole time course including the nulls is reported (Solid); the limitations paragraph is candid (Solid). Five Embellished: the evening framing has no morning arm, the 40 percent headline is a share of the baseline rise (18 percent of the value, 5 percent over two hours), the AUC units describe average glucose and the trapezoid spreads the 60-min drop back before the bout, the sample was never screened for diabetes despite the title, and the group's own one-minute nulls are cited as successes. Includes a back-of-envelope note that the glucose shift exceeds the ~7 kcal energy cost of the bout, a proofreading tally of six reporting errors, and a 12-study related-literature table showing a dose response with no acute benefit demonstrated in people with normal glucose. Adversarial pass: Grok 4.6 and GPT-5.2, authorship stripped. The Desperation Dial Two Nucleotides Single-source review of Takada, Yamahoki, Mifsud et al., Nature Communications, published 5 Sep 2026 (DOI 10.1038/s41467-026-77599-6; preprint bioRxiv 2025.10.24.684489), framed as Anti-Anti-Science. BRZ batCoV is a 30,386 nt betacoronavirus from a Pteronotus parnellii bat netted during government vampire-bat rabies control in Maranhao, Brazil, May-Aug 2019; 70 bats, only 2 were vampire bats; samples sat at -80C until submission in Nov 2025. Proposed sixth Betacoronavirus subgenus; closest relatives are two 816 nt RdRp fragments from Costa Rica (Corman 2013). FIVE CLAIMS SORTED. (1) New lineage from an undersampled region SOLID: 66.99% ORF1ab identity to hedgehog betaCoV, 65.8% marker-set identity to MERS-related CoV, spike tops out at 25.7% to HKU5; subgenus is a proposal, ICTV has not ruled. (2) Furin cleavage site experimentally validated SOLID: HEK293T expression, GSAS substitution abolishes cleavage, furin siRNA knockdown reduces it, human and bat furin rescue restores it, RaTG13 negative control; scope is plasmid-expressed truncated spike in a human kidney line, not virus. (3) 'One amino acid from SARS-CoV-2' MOSTLY SOLID and this is the core correction: RDAR vs RRAR differ at P3, arginine to aspartate, a charge reversal; RDAR is NOT polybasic (2 of 4 basic, one acidic) while RRAR is (3 of 4); at codon level Asp to Arg is a MINIMUM OF TWO nucleotide substitutions (GAC to CGC), so one amino acid is not one mutation. Architecturally BRZ batCoV is closer to MERS (RSVR) than to SARS-CoV-2. (4) What was not measured SOLID: no live virus, no pseudovirus, no receptor, no infectivity assay, no challenge; AlphaFold3 average pLDDT 58 (FCS region 78.89 monomer / 75.69 trimer); Boltz-2 model generated and excluded at TM-score 0.37; the paper itself states discussion of zoonotic potential 'should be limited'. (5) Host biology loose threads MOSTLY SOLID, both surfaced by adversarial verification: Pteronotus parnellii is a species complex (Pavan and Marroig 2016 proposed eight species; nominal parnellii is Jamaican; Brazilian populations are P. rubiginosus or an undescribed Amazonian lineage) and the ID was morphology-only, which the taxonomy literature says cannot resolve it; and the 'bat furin' used in rescue was P. mesoamericanus, a Central American congener, not the host species. ANTI-ANTI-SCIENCE CORE: a peer-reviewed letter in Rev Soc Bras Med Trop 59 (2026), DOI 10.1590/0037-8682-0583-2025, accepted March 2026 off the preprint, contains two errors both running toward alarm: it expands BRZ (which denotes Brazil) as 'bat-related zoonotic', and it calls the finding 'a polybasic furin cleavage site (RRAR)' when the motif is RDAR and is not polybasic. Four months from preprint to peer-reviewed distortion with no bad actor in the chain. EPISTEMICS SECTION: CIA Jan 2025 lab-origin assessment at low confidence, explicitly based on no new intelligence but a re-reading of existing reporting; FBI moderate confidence since 2021; DOE low confidence 2023; four agencies natural origin at low confidence; WHO SAGO 2025 zoonotic spillover as best supported. Same genome, different priors. The sequence carries no provenance, which is why the question is answerable only by epidemiology, sampling records and lab notebooks, i.e. the things that were not preserved. Both sides of the origins argument are given their strongest form: Wu and Zhao 2020, Sander 2022, Zhu 2023 (Bat CoV CD35), Garry PNAS 2022 on one side; the 2018 DEFUSE proposal on the other. Note DEFUSE targeted sarbecoviruses and BRZ batCoV is not one. AI Art of the Week: I Saw the Figure 4.93 in Gold The Curve Labelled Fusion Never The Vibes Are Not the Variable Matched for Water, Not for Volume Single-source review of Juett et al., J Int Soc Sports Nutr 23(1), published online 31 Aug 2026, DOI 10.1080/15502783.2026.2721140, CC BY, full text via PMC13532359. Randomized crossover, 17 completers (15M/2F, age 28+/-8), cycling at ~35C to ~2% body mass loss then rehydration with 150% of loss over 1h plus 4h rest. THE METHODOLOGICAL POINT: beverages matched for WATER volume via a macronutrient weight correction, not total volume, which is the confound in the prior literature (a 500 mL 6% sports drink holds at least 30 mL less water than 500 mL of water, so total-volume matching hands the water arm extra water and extra diuresis). Delivered water 2148/2119/2125 mL, P=0.580. RESULT: no difference in urine volume (1266/1338/1394 mL, P=0.156) or water retention (42/37/35%, P=0.059, right direction, not significant). Glucose AUC separated all three (10.12/12.48/7.90 mmol/L/2h, P<0.001, pairwise P<0.003), sports drink highest, water lowest. CAVEATS: 29 recruited and 12 withdrawn, including 3 with diarrhea after ~2,300 mL of juice in an hour; retrospectively registered NCT07468539; balance equations ignore sweat and insensible loss; 15 of 17 male; powered for 17 on a medium effect. FUNDING SITS CLOSE TO THE PRODUCT: Innovate UK KTP co-funded by Innate-Essence Limited, which makes Raw Hydrate and supplied it; first author employed on the KTP, second author on a company studentship; senior author has PepsiCo funding. Result is null for the sponsor's product against water. ORIGINAL ARITHMETIC ADDED BY WAiR: salt converted to sodium gives sports drink ~20 mmol/L and juice ~7 mmol/L, both far below the 60-75 mmol/L of oral rehydration solutions, so sodium is the variable that would have had to differ; and the juice arm carries ~2.9 g potassium, near 74 mmol, in one hour, unremarkable in healthy kidneys and a real load in reduced excretory capacity. CROSS-LINKS how-much-water-2026-08-03-v1 and JERKFoW #7 (hyponatremia/sodium as dilution), #8 (8x8 myth), #11 (concentrating ability). Built in the plain review format at Adam's request, no claim cards, no verdict tags, no adversarial pass. Daniel standard clean. The Last Word in Scientific Manufacture The Radiendocrinator, a gold plated radium device sold from 1924 to 1929 by American Endocrine Laboratories in New York, priced at $1,000 then $150, worn under the scrotum overnight via an adapter strap. Verified real against the ORAU Museum of Radiation and Radioactivity catalogue. The argument is that it was not sold against medicine but as the consumer edition of the era's most prestigious science: Steinach was nominated for the Nobel six times between 1921 and 1938, Voronoff was applauded by surgeons in London in 1923, insulin reached the clinic in 1922, and the company distributed a book titled Scientific Rejuvenation Without Operation. Documents the respectability laundering through Herman H. Rubin MD, expelled from the New York State and County medical societies in March 1924, who prescribed the identical device as the Rubin Endocrinator through Radisante Endocrine Laboratories, a renamed shell of the same company. ORIGINAL ANALYSIS: gonadal dose reconstruction from the single surviving ORAU specimen reading of ~200 mR/hr contact beta gamma, derated and bounded, against ICRP protracted thresholds of 0.4 Gy/y temporary and 2.0 Gy/y permanent sterility. Finding holds to roughly a 14x derating and fails past it, stated explicitly. Key radiobiological point: permanent sterility needs 3.5 to 6.0 Gy acute but only 2.0 Gy/y protracted, so nightly indefinite wear is the worst available delivery schedule for a device sold for virility. Ra-228 in the original stock and a century of radon leakage both push the 1920s device hotter than the measured one, flagged as open. Exhumation chronology for Bailey (1969 vs 1970 vs early 1960s) flagged as unresolved rather than asserted. DEDUP NOTE: Radithor and Eben Byers are deliberately NOT the spine here, having been used in montana-right-to-try-2026-08-01-v2; the Revigator and NIST 2010 were used in the 2026-03-23 issue Things I Learned. The Hunter Corpus All four volumes of The Complete Works of John Hunter, F.R.S. (ed. James F. Palmer, Philadelphia 1841), scanned by the National Library of Medicine, extracted and made searchable. 1.1 million words across the Life by Ottley, the surgical lectures, the teeth, the venereal treatise, blood and gunshot wounds, and the Animal Oeconomy. Twelve curated finds, including Hunter's 1760s plan to freeze people and thaw them out two centuries later, his instruction to Jenner to stop thinking and try the experiment, his own footnote admitting tooth transplantation succeeded once in a great number of trials, and the 1835 editor's footnote that appears to have invented the two-hundred-year-old legend that Hunter inoculated himself with venereal matter. The Label Was Backwards A Mendelian randomization study in npj Science of Food finds that unsweetened filter coffee tracks with more Veillonella, which tracks with lower HbA1c, and puts 43% of the effect through that one genus. The Cork feeding study, four months later and sharing no data or authors, found the same genus blooming when coffee was reintroduced. Two independent designs, one bacterium. The paper was also corrected by Nature because its results and tables had decaf and caffeinated labelled backwards, which is the exact axis the whole field turns on. Fifteen People on Decaf A viral post says researchers proved coffee drinkers have worse memory and that decaf is the real brain food. The paper underneath (Nature Communications, APC Microbiome Ireland, 62 Irish adults, ISIC funded) is a careful preregistered study that proves neither and says so. Six claims checked: the memory headline is a secondary outcome in fifteen people that the authors flag as a possible practice effect, the microbiome shifted in a handful of strains with no diversity change, mood questionnaires improved on either coffee while cortisol never moved, and the species that bloomed on reintroduction was Veillonella, not the ones the post named. Antitrust's System of Record Problem Five Percent Is a Lot of Chips Six Sides and a Jet Stream Every Last One Ed Yong reports the discovery of Falcopolis, a 1.5-square-mile roost in central Angola where a Hungarian ornithologist found where red-footed falcons go every March, after satellite-tagging 28 birds. The story holds and the reporting is careful. Three things checked: the Hungarian nest-box recovery is exactly as published; the one-million figure sits above every published estimate of the entire species and was an awed guess the headline hardened into a census; and every last one from Hungary to Kazakhstan is an extrapolation from 28 Hungarian birds across a range reaching the upper Lena. The article also never mentions that the IUCN uplisted this bird to Vulnerable in 2021. Includes the Nagaland Amur falcon precedent, where the same playbook took 12,000 to 14,000 birds killed per day to essentially zero in one year. Two and a Half Hours Version 2, written from the full text. A new npj Mental Health Research paper found the same screen-time signal in eleven independent annual samples of US adults, and the replication holds up under temporal validation. But the exposure variable is not measured minutes, it is the sum of 24 hourly probability sliders; the paper Table 1 puts gaming and internet use above social media; the abstract disagrees with the results table; and the study rank for its own headline variable is stated four incompatible ways. Six claims sorted, plus a correction to the first version of this review. Two and a Half Hours A new npj Mental Health Research paper found the same social media signal in eleven separate annual samples of American adults, total N around 183,000. The replication is the real contribution and nobody covered it. What got covered was an eleven-year cohort study that was never run and a 150-minute clinical threshold that does not exist. Four claims sorted, including a depression measure that sat on a 31-condition checklist between high blood pressure and corrective eyeglasses. The WAiR Podcast The permanent home of the AI-generated audio companion to the newsletter. The latest episode plays in the page, the six other self-hosted episodes since late July play inline, and all 70 earlier episodes back to October 2024 are listed and linked to Google Drive alongside the issue each was made from. 77 episodes, filterable by date. Updated every week at wair.ajwein.com/podcast. AI Art of the Week: A Barnes Ensemble Eight works, one per section of the newsletter, hung as a single Barnes Foundation ensemble: burlap wall, wrought iron in the gaps, a Pennsylvania German chest below. Renoir for the birthday dinner, Cezanne for the drug-cost accounting on a table that will not sit flat, Seurat for the variant proportions, Soutine for the kidney stone, Demuth for the 900-word controlled vocabulary, Degas for the wine marathon, a gold-ground panel for the hidden-physics cabal, and a Pippin gallery interior for the Barnes itself. One prompt, four models, four different walls. The first French Impressionist styles to run in 166 art weeks. Total Accountability, No Line Authority A reading list on the hardest job in a technical organization: one person owns the outcome and almost nobody who does the work reports to them. Four organizations converged on four different answers to the same problem. Toyota's shusa holds total accountability for a vehicle with no line authority over the engineers, by design. NASA's flight director holds absolute authority in the moment, backed by a front room of controllers and back rooms of specialists. NASA's Technical Authority exists because the first two models failed, and gives engineering, safety, and health an independently funded dissent chain that escalates two levels above the original decision. Amazon's single-threaded leader negotiates ownership boundaries in writing before the team exists, including what it does not own. Also covers the expertise trap (Goodall's evidence for expert leaders, Wiseman's accidental diminishers), collaborative overload, decision rights, coaching people to speak up and across using TeamSTEPPS and intent-based leadership, and how NASA disseminates what it learns. Twenty-eight sources, grouped and annotated. The Counterpoise The follow-up reading for this week's Anti-Anti-Science section, on the All-In interview with Eric Weinstein. Eighteen sources, each explained in plain language. The careful research agrees with much of what he says is broken and disagrees with what he says is breaking it. Peer review really is a recent, politically driven invention (Baldwin, Isis 2018). Progress per researcher really has fallen (Bloom et al., AER 2020). Physics really is stuck (Hossenfelder). But the single most cited proof that science stopped producing breakthroughs lost most of its effect on 12 August 2026, when Nature published a correction showing that database records missing their reference lists were being scored as the most original work possible. Removing them cuts the sixty-year decline by 87 percent in one database and 97 percent in the other. Part two covers the method he recommends, including Aslett et al. (Nature 2023), who found that searching online to check a false story raises belief in it, because the search box is where the manipulation happens. Cherry and Asparagus Fact-check of Foodpairing's explainer on the food pairing hypothesis, the claim that ingredients go together when they share volatile aroma compounds. Three of its load-bearing claims fail. The 80% of flavor is smell figure traces to a 1977 study using one odorant and one tastant, both sweet, and Charles Spence calls the percentages meaningless. The 10,000 odorant figure has no experiment under it, and the trillion-odor replacement was dismantled twice in eLife in 2015. The core hypothesis holds for Western recipe databases only. Ahn et al. 2011 found East Asian cuisines do the opposite, Jain et al. 2015 found negative pairing in all eight Indian regional cuisines, and Ahn's own analysis shows the Western effect loses significance after removing 13 ingredients starting with milk, butter and cocoa. The one sensory panel that tested the hypothesis on human noses, Bredie and Hartvig at Copenhagen with 53 binary mixtures, found no correlation between volatile overlap and pleasantness. The chemistry explains why: 10,000+ volatiles are known across foods but only about 230 are key odorants, and any one food is 3 to 40 of them. Cultured butter is 3, strawberry 12, cognac 36. The Savings Grow as the Sample Shrinks v2, supersedes v1. Adds analysis of Figures 1 through 4 from the typeset article, which the web version does not render. Three findings visible only in the panels: neither cost component reaches significance at 12-18 months in either analysis (IPCW medical -$211 p=0.065 plus pharmacy -$108 p=0.050 sums exactly to -$319 p=0.015; pairwise -$280 p=0.088 plus -$278 p=0.053 gives -$607 p=0.023); the control arm's non-tirzepatide pharmacy cost more than doubles from $227 to $477 in the final pairwise window at n=793, supplying 46 percent of the headline saving; and the inpatient/ED incidence rate ratio at 12-18 months pairwise is 0.99 (0.60-1.64) p=0.980, a flat null in the same window as the largest cost saving, which contradicts the stated mechanism. Also adds the Figure 1 cascade showing matching was done on the full adult population and the over-55 cohort retained as 9.2 percent of matched pairs, plus the null first window and the JAMA BALANCE commentary. The Savings Grow as the Sample Shrinks Eli Lilly funded, authored, and announced a Diabetes, Obesity and Metabolism study concluding that tirzepatide offsets its own $195 Medicare Bridge price by month twelve. Both cohorts start at 15,843; by the window carrying the policy conclusion, 1,181 treated patients remain, and the effect size grows in step with the attrition. Covers the one-armed discontinuation censoring, what propensity matching could and could not see, the gap between a cohort with mean age 64.5 and a program for 65-plus, the NBER study of 537,000 initiators that found no offsets and that the paper cites as its own refutation, and the six-month timeline shift between the paper's conclusion and the press release. Simulated The pregnancy in space study behind this week's coverage was run in a dual axis clinostat in Adelaide, not in orbit. The machine does not remove gravity, it randomizes the vector faster than a cell can integrate it. The paper's strongest section is the control work proving the box was not simply stirring the sample: rotational controls, fluorescent bead tracing, and a reported 20% curvilinear velocity drop in the control that did not appear in the treatment. Human sperm traversed the channel less often (P=0.002, P=0.007) with motility unchanged, pointing at orientation rather than propulsion. Three errors in the National Geographic coverage: the 30 to 50 percent maze figure appears nowhere in the paper, the progesterone rescue required 100 micromolar against picomolar physiology, and SJ-10 launched April 2016 with two cell embryos while the Ronca rats flew on shuttle missions, not the ISS. The authors disclose that their clinostat is a proprietary Firefly Biotech device and flag it as a reproducibility limitation. The finding worth keeping never leaves Earth: microgravity acted as a selection filter, and the sperm that made it bound hyaluronan better (P=0.04). Two Controlled Languages v2. The Nature Human Behaviour paper on LLM homogenization, now set against the Druckenmiller WSJ op-ed that got caught by Pangram within hours of publication. Adds a three-way comparison of ASD-STE100, Orwell's six rules, and LLM polishing, plus five working rules for writing with AI that sit between the aerospace standard and no constraint at all. Two Controlled Languages A Nature Human Behaviour paper (published 24 Aug 2026) measures how LLM polishing flattens writing-complexity variance by 21 to 50 percent while preserving meaning, and strips the markers that identify an author. Set against ASD-STE100 Simplified Technical English, the aerospace standard that removes the same variance on purpose and says where it stops. Includes the gap between this lab's 2024 preprint ("slightly," "infrequent") and the 2026 title. The Canary and the Appendix The August 2026 revision of Brynjolfsson, Chandar and Chen's ADP payroll study through June 2026. The headline kept-pace gap for 22 to 25 year olds in AI-exposed occupations widened from 16 to 19 percent, while Appendix L discloses that the within-firm Poisson estimate for the most exposed quintile fell from 11.7 to 5.3 log points and lost significance when the old specification is applied to the new data. Covers the hiring-not-firing finding, the automation vs complementarity age gradient from the Anthropic Economic Index, the education control that halves the effect, and the ADP vs ACS sector split where education, health and public administration come out with opposite signs. Where Thought Process Ends and Wisdom Begins Twenty five essays from Every's Thesis Statements series on work after automation, read against the FDA's August 2026 discussion paper on testing generative AI medical devices (docket FDA-2026-N-7874). Four boundary lines where automatable thought ends (explicitness, verifiability, question framing, embodiment), one building code for the edge, and the case that epistemic humility is becoming a regulatory test requirement. WAiR Podcast: Why Algorithms Struggle With Human Biology A 23-minute AI-generated discussion of this week's issue, produced with NotebookLM. The melanoma readout with no numbers, a quantum claim undone in three weeks, screening you cannot unknow, and the FDA testing machines like clinicians. AI Art of the Week, Paint My Numbers One prompt, four models. An unfinished paint-by-numbers canvas where filled regions are what we know, numbered outlines are what was published but unconfirmed, and three regions carry no number at all. Classifier, Not Translator Eight viral claims that AI is decoding animal language, checked one at a time against the papers. Six hold, one invents its most impressive detail, and the only case where a human ever sent a message an animal acted on is a robot bee with no AI in it at all. Proving You Ran It IBM ran a quantum computation no classical machine can check, then proved a floor on how well it ran. The certificate is the contribution, the fifteen-minute headline is not, and the press has confused error detection with error correction. The Color Is Not Yours The Channel Nobody Claimed A viral post says some women see colors nobody else can. The paper found one such woman in twenty-four. Meanwhile a 1956 Moscow experiment shows everyone has a fourth color channel in peripheral vision and nobody uses that either. When the Screening Comes to You The practical companion to this week's issue. Incentivized screening, what the incentive is actually measuring, and why the genetic panel is the one item you cannot return. The FDA Writes a Board Exam CDRH proposes credentialing generative AI devices like clinicians. What the discussion paper actually says, and where the analogy breaks. Tell It Where It Is The Vial That Fits One Person Merck and Moderna said their individualized mRNA cancer vaccine met its Phase 3 endpoints and released no numbers. The stock had its best day ever. What holds up, what does not, and the 2024 FDA decision nobody wrote about. The Poll Answers Its Own Question The Afterlife of Corporate Swag The Parable That Ate Rapa Nui AI Art of the Week: Mid-Century Modernist Screen-Print Three Legal Drugs and a Rowing Machine The Price of a Body GLP-1 Agonists and Alzheimer's: Three Tiers of Evidence That Disagree The Universe Runs Zip, and Other Claims The Claim That Survives The Agents Caught a Cold When the Vendor Pays Your Reference Claudius Learned to Run the Shop WAiR Podcast: Sleeper Viruses and the Mental Password AI Art of the Week: Anatomical Fugitive Sheet A College Student's Odyssey The Viruses You Already Have A Trial of One Graveyards of Giant Pandas at the Bottom of the Sea The Number That Gives It Away The Researcher Who Left OpenAI to Build Telepathy The Librarian and the Reader What the Daddy Longlegs Headline Left Out The Benchmark Says Gemini. The Clinic Says Wait. How Much Water Should You Drink? AI Art of the Week: Haeckel — Kunstformen der Woche Off the Color Wheel: Seeing a Color That Isn't There Inner Light: The Faint Glow of Being Alive Should We Lock the Clock on Daylight Saving Time? The AHA Comes Out for Coffee Kelly, the Sassy Dolphin Montana Reopens the Patent Medicine Store Futuristic Medicine Meets Messy Human Reality AI Art of the Week: Norman Rockwell Saturday Evening Post Covers AI Art Prompt: Norman Rockwell Saturday Evening Post Covers Why Five Fingers? The FDA Cleared Six Peptides for Compounding. The Evidence Didn't. Supercooled Kidneys, Warm Optimism Supercooled Kidneys, Warm Optimism Science: A New Golden Age Science: AI-designed RNA-guided nucleases (SynTnpB) First, Do NOHARM First, Do NOHARM Seven in Ten Americans Don't Want a Data Center Next Door Creatine and Cancer: The NHANES Evidence Three Infections, Three Warnings The Turbo Cancer Claim Comes Back With Credentials Attached Biological Aging Clocks: Wyss-Coray & Topol in Nature Medicine Space Bioprinting & Interstellar Sugar